In response to unexpectedly low enrollment, the protocol was amended in October 2008 to improve the primary outcome from a binary result to a continuing outcome in order to raise the power of the analysis. Funding constraints mandated closing enrollment prior to the revised sample-size target of 450 was reached. Secondary outcomes included radiographic progression ; the proportion of individuals with a DAS28 of 3.2 or much less, a value that’s consistent with low disease activity29; American University of Radiology 20, 50, and 70 responses, indicating 20 percent, 50 percent, and 70 percent reductions, respectively, in the number of both tender and swollen joints and comparative improvement in at least three of five additional requirements31; responses on the Clinical Disease Activity Index, which really is a composite score of the sum of tender and swollen joints and the individual and physician global assessments 32; and useful outcomes, as measured with the use of the ongoing health Assessment Questionnaire II.The price of stent thrombosis was similar with the three anticlotting regimens tested in the ACUITY trial. The incidence of stent thrombosis is usually a critically relevant topic today, in high-risk individuals with acute coronary syndromes especially, said Dr. Stone. These data, carefully collected and adjudicated by a committee blinded to stent type, provide reassuring proof that long-term stent thrombosis prices are not higher with drug-eluting stents in comparison with bare metal stents, Dr. Stone said. Dr. Stone will show the one-year outcomes of the ACUITY trial at a Later Breaking Clinical Trials session on Monday, March 26, at 2 p.m.