The longest duration of support with these devices in each of these two groups was 192 days and 28 days, respectively. Among participants in cohort 1, the median time to the primary end point hadn’t yet been reached at 174 days. In contrast, the median time to the principal end stage in the matched ECMO group was 13 times . Among individuals in cohort 2, the median time to the primary end point was 144 days, in comparison with 10 times in the matched ECMO group .In the United States, weight problems is estimated to cause 111,909 to 365,000 deaths each year. Normally, obesity reduces life expectancy by six to seven years, while severe weight problems, characterized as a BMI greater than 40, reduces life span by 10 years. The CDC reviews that 60 million Americans age 20 and old are obese, with African Hispanics and Us citizens having a greater prevalence of obesity than non-Hispanic whites. Past attempts to contain weight problems as a public and lifestyle phenomenon have failed and have led the country to the point of epidemic obesity in our country. Based on accumulating scientific evidence, AACE concludes that the condition of obesity should be addressed utilizing a robust medical model for treatment and prevention which includes lifestyle modifications, medications, and surgery as well as interventions targeted to public education, behavioral modification, and the constructed environment.