All-Cause Mortality By the finish of the study, 354 guys had died . Among guys in the radical-prostatectomy group, 171 died, as compared with 183 in the observation group . Median survival was 13.0 years in the radical-prostatectomy group and 12.4 years in the observation group. At 12 years, 40.9 percent of men assigned to radical prostatectomy and 43.9 percent of those assigned to observation had died. The absolute reduction in mortality with radical prostatectomy had not been significant at any interval and declined as time passes, from 4.2 to 9.3) at 4 years to 2.2 to 10.0) at 12 years.Associations between coffee drinking and the chance of death from cardiovascular disease have been particularly controversial, and several research have suggested an elevated risk among espresso drinkers.9,10 Even so, the inverse associations observed in our research are consistent with those in a recently available meta-analysis of this association. In that analysis, the relative risk of death among guys in the highest category of coffee consumption, in comparison with guys in the lowest category of coffee consumption, was 0.89 .10 Although some previous studies showed differences in risk according to the interval between baseline and the time of death,9 we observed similar associations for deaths occurring late or early in follow-up.