Taking more than directed can be an overdose and can result in liver damage. The U.S. Food and Medication Administration has established a maximum daily dose of 4,000 milligrams of acetaminophen in a 24-hour period. The Coalition advises chilly and flu sufferers to follow four key acetaminophen secure use steps: Often read and follow the medication label. Check labels on all your medicines for acetaminophen, which can be listed on the front panel of product packaging and in bold type or highlighted in the ‘active ingredients’ portion of OTC medicine labels, and sometimes detailed as ‘APAP’ or ‘acetam’ on prescription labels.He slumped around, shirt half-untucked, perpetually pulling a yellowed handkerchief from his pocket to clean his perspiring forehead. Everyone concerned he was ill. His problem, however, turned out to be the electronic health record . Investigating the root causes, Wachter discovers design flaws, such as defaulting to certain units for medicine dosing and alerts rendered meaningless by their sheer quantity. But he concludes that the mistake stemmed much less from the EHR itself than from its effects on our collective psychology.