The pale areas within the mole separating the network matched the colour of the encompassing skin. There is no evidence of scarring. Excision biopsy showed an epidermis with a prominent but irregular pigmented rete ridge program of differing lengths and a diffuse sheet of benign naevus cells in the underlying dermis .. A mole with a broken pigment network A broken and coarse pigment network might reflect the current presence of a dermal component which has effaced the rete ridges. Case presentation A 34-year-old man presented with a 1.2 x 0.9 cm, irregularly pigmented, smooth mole of unknown duration on his spine .2012 coding books consist of: ICD-9-CM Professional for Physicians Vol.1-2ICD-9-CM Professional for Hospitals Vol. These programs include 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and Choline Kinase . Action obtained worldwide exceptional licenses from the Brown Cancer Center to the PFKFB program in 2008 and for the CK program in 2009. To date, ACT has designed and synthesized over 200 novel rationally small molecule compounds against both PFKFB and CK targets. The company has been capable to identify several potential preclinical candidates with preferred potency and selectivity parameters and other appealing attributes, bringing them nearer to initiating toxicology research that would support an investigational brand-new drug application.