Variant Creutzfeldt-Jakob Disease is normally distinguished from the classical type by its early onset and a predominance of psychiatric and sensory symptoms. The prions in this type are usually transmitted by consuming the meats of bovines with so-known as mad cow disease , although there is no definite proof this association up to now. Nevertheless over 95 percent of identified cases of vCJD are in Britain. BSE is certainly a chronic progressive degenerative disease impacting the central nervous program of cattle. There is no treatment, and affected cattle die. BSE is classified as a transmissible spongiform encephalopathy . The causative agent for BSE has not been determined... Albireo reports positive results from A3309 Phase IIb study in chronic idiopathic constipation Albireo today announced positive top-line results from a Stage IIb research in chronic idiopathic constipation assessing efficacy and security of three different dosage amounts of the investigational drug A3309 during an eight week trial. Analyses of the info present clinically meaningful and statistically significant improvement for individuals treated with A3309 in comparison to placebo-treated patients. A3309 is normally a first-in-course IBAT inhibitor with reduced systemic exposure which is created for the treatment of CIC and constipation-predominant irritable bowel syndrome .